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KMID : 0363220110490010062
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Korean Journal of Dermatology
2011 Volume.49 No. 1 p.62 ~ p.67
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Three Cases of Churg-Strauss Syndrome Diagnosed after Presence of Cutaneous Manifestation
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Kim Tae-Wook
Song Margaret
Park Hyun-Je
Kim Hoon-Soo
Kim Su-Han
Ko Hyun-Chang
Kim Byung-Soo
Kim Moon-Bum
Kwon Kyung-Sool
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Abstract
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Churg-Strauss syndrome (CSS) is an uncommon disorder that is characterized by asthma or allergic rhinitis, fever, systemic vasculitis, extravascular granulomas and hypereosinophilia. Cutaneous manifestations of CSS are one of the most common extra-pulmonary findings, and they occur in approximately 60% of the cases. Other manifestations include pulmonary infiltrates and heart, kidney, gastrointestinal tract, peripheral and central nervous system involvement and the patients also complain of systemic symptoms, including malaise, fever, myalgia and weight loss. The diagnosis of CSS is difficult because the manifestations vary with the disease stage and delayed treatment can lead to fatal major organ damage. We report here on 3 cases of CSS that were first diagnosed by the dermatologic department and with consultation from other departments. So, we want to remind dermatologists that if the patients of asthma or other allergic diseases have purpuric skin lesion, then CSS should be included in the differential diagnosis.
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KEYWORD
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Churg-Strauss syndrome, Vasculitis
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